Giant wasps have a poisonous stinger that delivers a paralysing venom. Any creature hit by the stinger must make a saving throw vs poison or become paralysed for 1d4+1 days, followed by death. The wasps generally carry paralysed victims to their nests, where the victims are kept to be eaten by larvae when eggs hatch. Giant wasp nests may be mud-daubed or paper, depending on the type of wasp. Giant wasp wings are instantly burned away if they suffer a successful hit with a flaming object; burning away the wings in this manner does not cause hit point damage to the wasp, but prevents the creature from flying.

Although giant wasps are aerial agility level V, they can hover.